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Mechanistic Evaluation of the Effect of Sintering on Compritol® 888 ATO Matrices

The present research studied the effect of sintering technique in the development of a controlled release formulation for ketorolac tromethamine. The method consisted of mixing drug and wax powder (Compritol® 888 ATO) along with lactose as diluent and talc as lubricant followed by direct compression...

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Detalhes bibliográficos
Main Authors: Rao, Monica, Ranpise, Anuradha, Borate, Sameer, Thanki, Kaushik
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690774/
https://ncbi.nlm.nih.gov/pubmed/19333763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9211-8
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