Clinical Effect of Point Mutations in Myelodysplastic Syndromes

BACKGROUND: Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired differentiation, peripheral-blood cytopenias, and a risk of progression to acute myeloid leukemia. Somatic mutations may influence the clinical phenotype but are not included...

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Autores principales: Bejar, Rafael, Stevenson, Kristen, Abdel-Wahab, Omar, Galili, Naomi, Nilsson, Björn, Garcia-Manero, Guillermo, Kantarjian, Hagop, Raza, Azra, Levine, Ross L., Neuberg, Donna, Ebert, Benjamin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159042/
https://ncbi.nlm.nih.gov/pubmed/21714648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1013343
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