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Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes
Somatically acquired genetic abnormalities lead to the salient features that define myelodysplastic syndromes (MDS): clonal hematopoiesis, aberrant differentiation, peripheral cytopenias, and risk of progression to acute myeloid leukemia. Although specific karyotypic abnormalities have been linked t...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Clinical Oncology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969457/ https://ncbi.nlm.nih.gov/pubmed/21220588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.1175 |
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