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Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes

Somatically acquired genetic abnormalities lead to the salient features that define myelodysplastic syndromes (MDS): clonal hematopoiesis, aberrant differentiation, peripheral cytopenias, and risk of progression to acute myeloid leukemia. Although specific karyotypic abnormalities have been linked t...

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Détails bibliographiques
Auteurs principaux: Bejar, Rafael, Levine, Ross, Ebert, Benjamin L.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969457/
https://ncbi.nlm.nih.gov/pubmed/21220588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.31.1175
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