TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations

High incidence of HCC is mostly due to the combination of two major risk factors, chronic infection with hepatitis B (HBV) and/or C (HCV) viruses and exposure to the mycotoxin aflatoxin B(1), which induces a particular mutation at codon 249 in TP53 (R249S). Eight genotypes of HBV are diversely found...

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Hlavní autoři: Abedi-Ardekani, Behnoush, Gouas, Doriane, Villar, Stephanie, Sotoudeh, Masoud, Hainaut, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159019/
https://ncbi.nlm.nih.gov/pubmed/21869931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/475965
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