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Expedient Synthesis of N-Acyl Anthranilamides and β-Enamine Amides by the Rh(III)-Catalyzed Amidation of Aryl and Vinyl C–H Bonds with Isocyanates

A Rh(III)-catalyzed protocol for the amidation of anilide and enamide C–H bonds with isocyanates has been developed. This method provides direct and efficient syntheses of N-acyl anthranilamides, enamine amides, and pyrimidin-4-one heterocycles.

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Detalhes bibliográficos
Main Authors: Hesp, Kevin D., Bergman, Robert G., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158987/
https://ncbi.nlm.nih.gov/pubmed/21714533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203495c
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