Piroxicam Reverses Endotoxin-Induced Hypotension in Rats: Contribution of Vasoactive Eicosanoids and Nitric Oxide

Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin-induced vascular hyporeactivity and hypotension resulting in multiple organ failure. Endotoxic shock is also characterized by decreased expression of constitutive cyclooxygenase (COX-1), cytochrome P450 (CYP) 4A...

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Autores principales: Buharalioglu, C. Kemal, Korkmaz, Belma, Cuez, Tuba, Sahan-Firat, Seyhan, Sari, Ayşe Nihal, Malik, Kafait U., Tunctan, Bahar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158973/
https://ncbi.nlm.nih.gov/pubmed/21463481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-7843.2011.00708.x
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