Characterisation of Genome-Wide Association Epistasis Signals for Serum Uric Acid in Human Population Isolates

Genome-wide association (GWA) studies have identified a number of loci underlying variation in human serum uric acid (SUA) levels with the SLC2A9 gene having the largest effect identified so far. Gene-gene interactions (epistasis) are largely unexplored in these GWA studies. We performed a full pair...

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Main Authors: Wei, Wenhua, Hemani, Gibran, Hicks, Andrew A., Vitart, Veronique, Cabrera-Cardenas, Claudia, Navarro, Pau, Huffman, Jennifer, Hayward, Caroline, Knott, Sara A., Rudan, Igor, Pramstaller, Peter P., Wild, Sarah H., Wilson, James F., Campbell, Harry, Dunlop, Malcolm G., Hastie, Nicholas, Wright, Alan F., Haley, Chris S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158795/
https://ncbi.nlm.nih.gov/pubmed/21886828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023836
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