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Analysis of Factors Lowering Sensitivity of Interferon-γ Release Assay for Tuberculosis

BACKGROUND: Imperfect sensitivity of interferon-γ release assay (IGRA) is a potential problem to detect tuberculosis. We made a thorough investigation of the factors that can lead to false negativity of IGRA. METHODS: We recruited 543 patients with new smear-positive pulmonary tuberculosis in Hanoi,...

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Autori principali: Hang, Nguyen Thi Le, Lien, Luu Thi, Kobayashi, Nobuyuki, Shimbo, Takuro, Sakurada, Shinsaku, Thuong, Pham Huu, Hong, Le Thi, Tam, Do Bang, Hijikata, Minako, Matsushita, Ikumi, Hung, Nguyen Van, Higuchi, Kazue, Harada, Nobuyuki, Keicho, Naoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158775/
https://ncbi.nlm.nih.gov/pubmed/21886824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023806
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