Analysis of Factors Lowering Sensitivity of Interferon-γ Release Assay for Tuberculosis

BACKGROUND: Imperfect sensitivity of interferon-γ release assay (IGRA) is a potential problem to detect tuberculosis. We made a thorough investigation of the factors that can lead to false negativity of IGRA. METHODS: We recruited 543 patients with new smear-positive pulmonary tuberculosis in Hanoi,...

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Main Authors: Hang, Nguyen Thi Le, Lien, Luu Thi, Kobayashi, Nobuyuki, Shimbo, Takuro, Sakurada, Shinsaku, Thuong, Pham Huu, Hong, Le Thi, Tam, Do Bang, Hijikata, Minako, Matsushita, Ikumi, Hung, Nguyen Van, Higuchi, Kazue, Harada, Nobuyuki, Keicho, Naoto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158775/
https://ncbi.nlm.nih.gov/pubmed/21886824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023806
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