Analysis of factors lowering sensitivity of interferon-γ release assay for tuberculosis.

BACKGROUND: Imperfect sensitivity of interferon-γ release assay (IGRA) is a potential problem to detect tuberculosis. We made a thorough investigation of the factors that can lead to false negativity of IGRA. METHODS: We recruited 543 patients with new smear-positive pulmonary tuberculosis in Hanoi,...

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Detalhes bibliográficos
Main Authors: Nguyen Thi Le Hang, Luu Thi Lien, Nobuyuki Kobayashi, Takuro Shimbo, Shinsaku Sakurada, Pham Huu Thuong, Le Thi Hong, Do Bang Tam, Minako Hijikata, Ikumi Matsushita, Nguyen Van Hung, Kazue Higuchi, Nobuyuki Harada, Naoto Keicho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3158775?pdf=render
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