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Protein Diffusion in Mammalian Cell Cytoplasm

We introduce a new method for mesoscopic modeling of protein diffusion in an entire cell. This method is based on the construction of a three-dimensional digital model cell from confocal microscopy data. The model cell is segmented into the cytoplasm, nucleus, plasma membrane, and nuclear envelope,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kühn, Thomas, Ihalainen, Teemu O., Hyväluoma, Jari, Dross, Nicolas, Willman, Sami F., Langowski, Jörg, Vihinen-Ranta, Maija, Timonen, Jussi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158749/
https://ncbi.nlm.nih.gov/pubmed/21886771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022962
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