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The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases

TNF-related apoptosis inducing ligand (TRAIL) is a key mediator of the innate immune response to infection. While TRAIL-mediated apoptosis plays an essential role in the clearance of virus-infected cells, its physiologic role also includes immunosurveilance for cancer cells. Therapeutics that induce...

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Bibliografiske detaljer
Main Authors: Shepard, Brett D., Badley, Andrew D.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158564/
https://ncbi.nlm.nih.gov/pubmed/21857885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/187152109787846060
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