Quantitative characterization and analysis of the dynamic NF-κB response in microglia

BACKGROUND: Activation of the NF-κB transcription factor and its associated gene expression in microglia is a key component in the response to brain injury. Its activation is dynamic and is part of a network of biochemical species with multiple feedback regulatory mechanisms. Mathematical modeling,...

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Bibliographic Details
Main Authors: Sheppard, Patrick W, Sun, Xiaoyun, Emery, John F, Giffard, Rona G, Khammash, Mustafa
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158563/
https://ncbi.nlm.nih.gov/pubmed/21729324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-276
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