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Reduced production of B-1–specified common lymphoid progenitors results in diminished potential of adult marrow to generate B-1 cells

B-1 B cells have been proposed to be preferentially generated from fetal progenitors, but this view is challenged by studies concluding that B-1 production is sustained throughout adult life. To address this controversy, we compared the efficiency with which hematopoietic stem cells (HSCs) and commo...

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Autors principals: Barber, Chad L., Montecino-Rodriguez, Encarnacion, Dorshkind, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158209/
https://ncbi.nlm.nih.gov/pubmed/21808010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107172108
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