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Reduced production of B-1–specified common lymphoid progenitors results in diminished potential of adult marrow to generate B-1 cells
B-1 B cells have been proposed to be preferentially generated from fetal progenitors, but this view is challenged by studies concluding that B-1 production is sustained throughout adult life. To address this controversy, we compared the efficiency with which hematopoietic stem cells (HSCs) and commo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158209/ https://ncbi.nlm.nih.gov/pubmed/21808010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107172108 |
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