Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas

The transcription factor interferon regulatory factor 6 (IRF6) regulates craniofacial development and epidermal proliferation. We recently showed that IRF6 is a component of a regulatory feedback loop that controls the proliferative potential of epidermal cells. IRF6 is transcriptionally activated b...

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Detalhes bibliográficos
Principais autores: Botti, Elisabetta, Spallone, Giulia, Moretti, Francesca, Marinari, Barbara, Pinetti, Valentina, Galanti, Sergio, De Meo, Paolo D'Onorio, De Nicola, Francesca, Ganci, Federica, Castrignanò, Tiziana, Pesole, Graziano, Chimenti, Sergio, Guerrini, Luisa, Fanciulli, Maurizio, Blandino, Giovanni, Karin, Michael, Costanzo, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158164/
https://ncbi.nlm.nih.gov/pubmed/21807998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110931108
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