Characterization of antigenic variants of hepatitis C virus in immune evasion

BACKGROUND: Antigenic variation is an effective way by which viruses evade host immune defense leading to viral persistence. Little is known about the inhibitory mechanisms of viral variants on CD4 T cell functions. RESULTS: Using sythetic peptides of a HLA-DRB1*15-restricted CD4 epitope derived fro...

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Bibliografiske detaljer
Main Authors: Wang, Jane H, Pianko, Matthew J, Ke, Xiaogang, Herskovic, Alex, Hershow, Ronald, Cotler, Scott J, Chen, Weijin, Chen, Zheng W, Rong, Lijun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158126/
https://ncbi.nlm.nih.gov/pubmed/21801418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-377
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