BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

The deafness locus DFNB1 contains GJB2, the gene encoding connexin26 and GJB6, encoding connexin30, which appear to be coordinately regulated in the inner ear. In this work, we investigated the expression and function of connexin26 and connexin30 from postnatal day 5 to adult age in double transgeni...

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Xehetasun bibliografikoak
Egile Nagusiak: Crispino, Giulia, Di Pasquale, Giovanni, Scimemi, Pietro, Rodriguez, Laura, Galindo Ramirez, Fabian, De Siati, Romolo Daniele, Santarelli, Rosa Maria, Arslan, Edoardo, Bortolozzi, Mario, Chiorini, John A., Mammano, Fabio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158073/
https://ncbi.nlm.nih.gov/pubmed/21876744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023279
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