17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli

Detection and clearance of bacterial infection require balanced effector and resolution signals to avoid chronic inflammation. Detection of GNB LPS by TLR4 on mϕ induces inflammatory responses, contributing to chronic inflammation and tissue injury. LXs and Rvs are endogenous lipid mediators that en...

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Autors principals: Palmer, Christine D., Mancuso, Christy J., Weiss, Jerrold P., Serhan, Charles N., Guinan, Eva C., Levy, Ofer
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2011
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157902/
https://ncbi.nlm.nih.gov/pubmed/21653234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0311145
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