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Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice

MCs are required for an effective host response during septic peritonitis. Local MC degranulation facilitates neutrophil recruitment, activation, and bacterial killing. However, the role of MCs located distant from the site of infection is unknown. We studied the temporal and spacial degranulation o...

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Bibliografiska uppgifter
Huvudupphovsmän: Seeley, Eric J., Sutherland, Rachel E., Kim, Sophia S., Wolters, Paul J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Leukocyte Biology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157900/
https://ncbi.nlm.nih.gov/pubmed/21653231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0910531
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