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Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice

MCs are required for an effective host response during septic peritonitis. Local MC degranulation facilitates neutrophil recruitment, activation, and bacterial killing. However, the role of MCs located distant from the site of infection is unknown. We studied the temporal and spacial degranulation o...

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Detalhes bibliográficos
Main Authors: Seeley, Eric J., Sutherland, Rachel E., Kim, Sophia S., Wolters, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157900/
https://ncbi.nlm.nih.gov/pubmed/21653231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0910531
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