Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration

Enhanced S-cone syndrome (ESCS), featuring an excess number of S cones, manifests as a progressive retinal degeneration that leads to blindness. Here, through optical imaging, we identified an abnormal interface between photoreceptors and the retinal pigment epithelium (RPE) in 9 patients with ESCS....

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Detalhes bibliográficos
Main Authors: Mustafi, Debarshi, Kevany, Brian M., Genoud, Christel, Okano, Kiichiro, Cideciyan, Artur V., Sumaroka, Alexander, Roman, Alejandro J., Jacobson, Samuel G., Engel, Andreas, Adams, Mark D., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157681/
https://ncbi.nlm.nih.gov/pubmed/21659555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-186767
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