Genomic Changes in Gliomas Detected Using Single Nucleotide Polymorphism Array in Formalin-Fixed, Paraffin-Embedded Tissue: Superior Results Compared with Microsatellite Analysis

Deletion or loss of heterozygosity (LOH) in chromosomes 1p and 19q in oligodendrogliomas (ODGs) have diagnostic, prognostic, and therapeutic implications. Current clinical assays are limited because the probes or primers interrogate only limited genomic segments. We investigated the use of single nu...

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Detalhes bibliográficos
Main Authors: Harada, Shuko, Henderson, Lindsay B., Eshleman, James R., Gocke, Christopher D., Burger, Peter, Griffin, Constance A., Batista, Denise A.S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157617/
https://ncbi.nlm.nih.gov/pubmed/21726663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.05.009
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