Comparison of Allelic Discrimination by dHPLC, HRM, and TaqMan in the Detection of BRAF Mutation V600E

The V600E mutation in the BRAF oncogene is associated with colorectal carcinomas, with mismatch-repair deficiency and, recently, with nonresponse to epidermal growth factor receptor inhibitor therapy. The use of reliable techniques for its detection is important. The aim of our study was to compare...

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Detalhes bibliográficos
Main Authors: Carbonell, Pablo, Turpin, María C., Torres-Moreno, Daniel, Molina-Martínez, Irene, García-Solano, José, Perez-Guillermo, Miguel, Conesa-Zamora, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157612/
https://ncbi.nlm.nih.gov/pubmed/21708284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.03.009
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