Comparison of Allelic Discrimination by dHPLC, HRM, and TaqMan in the Detection of BRAF Mutation V600E

The V600E mutation in the BRAF oncogene is associated with colorectal carcinomas, with mismatch-repair deficiency and, recently, with nonresponse to epidermal growth factor receptor inhibitor therapy. The use of reliable techniques for its detection is important. The aim of our study was to compare...

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Dettagli Bibliografici
Autori principali: Carbonell, Pablo, Turpin, María C., Torres-Moreno, Daniel, Molina-Martínez, Irene, García-Solano, José, Perez-Guillermo, Miguel, Conesa-Zamora, Pablo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157612/
https://ncbi.nlm.nih.gov/pubmed/21708284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.03.009
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