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A Multiplex SNaPshot Assay as a Rapid Method for Detecting KRAS and BRAF Mutations in Advanced Colorectal Cancers

The analysis of KRAS mutations has become a prerequisite for anti-epidermal growth factor receptor therapy in patients with metastatic colorectal cancers. KRAS mutations are associated with resistance to treatment by monoclonal antibodies such as cetuximab and panitumumab and thus are correlated wit...

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Bibliografski detalji
Glavni autori: Magnin, Sandrine, Viel, Erika, Baraquin, Alice, Valmary-Degano, Severine, Kantelip, Bernadette, Pretet, Jean-Luc, Mougin, Christiane, Bigand, Marthe, Girardo, Benoît, Borg, Christophe, Ferrand, Christophe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157611/
https://ncbi.nlm.nih.gov/pubmed/21742054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.05.010
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