A Multiplex SNaPshot Assay as a Rapid Method for Detecting KRAS and BRAF Mutations in Advanced Colorectal Cancers

The analysis of KRAS mutations has become a prerequisite for anti-epidermal growth factor receptor therapy in patients with metastatic colorectal cancers. KRAS mutations are associated with resistance to treatment by monoclonal antibodies such as cetuximab and panitumumab and thus are correlated wit...

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Detalhes bibliográficos
Main Authors: Magnin, Sandrine, Viel, Erika, Baraquin, Alice, Valmary-Degano, Severine, Kantelip, Bernadette, Pretet, Jean-Luc, Mougin, Christiane, Bigand, Marthe, Girardo, Benoît, Borg, Christophe, Ferrand, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157611/
https://ncbi.nlm.nih.gov/pubmed/21742054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.05.010
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