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Targeted, Activatable, IN VIVO Fluorescence Imaging of Prostate-specific Membrane Antigen (PSMA)-positive Tumors Using the Quenched Humanized J591 Antibody-ICG Conjugate

In patients with prostate cancer, a positive surgical margin is associated with an increased risk of cancer recurrence and poorer outcome, yet, margin status cannot be determined during the surgery. An in vivo optical imaging probe that could identify the tumor margins, during surgery, could result...

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Detalhes bibliográficos
Main Authors: Nakajima, Takahito, Mitsunaga, Makoto, Bander, Neil H., Heston, Warren D., Choyke, Peter L., Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157565/
https://ncbi.nlm.nih.gov/pubmed/21740058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc2002715
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