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Expression of the active Notch1 decreases MTC tumor growth in vivo
BACKGROUND: Human medullary thyroid cancer (MTC), is a neuroendocrine (NE) tumor, derived from thyroid C-cells. Besides surgery, there are no curative therapies for MTC. This emphasizes the need for the development of new therapies. In MTC, Notch1 signaling pathway is absent and Notch1 activation in...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157562/ https://ncbi.nlm.nih.gov/pubmed/21571316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.03.035 |
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