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Chrysin Activates Notch1 Signaling and Suppresses Tumor Growth of Anaplastic Thyroid Carcinoma In vitro and In vivo

BACKGROUND: Anaplastic thyroid cancer (ATC) is a very aggressive thyroid gland malignancy with very poor prognosis. We suspect that the Notch signaling pathway, which is not active in ATC, may have a tumor suppressor function in this neoplasm. However, it remains unknown whether activation of Notch...

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Autores principales: Yu, Xiao-Min, Phan, TramAnh, Patel, Priyesh N., Jaskula-Sztul, Renata, Chen, Herbert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528831/
https://ncbi.nlm.nih.gov/pubmed/22991264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27742
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