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Spider Silk-Based Gene Carriers for Tumor Cell-Specific Delivery

The present study demonstrates pDNA complexes of recombinant silk proteins containing poly(L-lysine) and tumor-homing peptides (THPs), which are globular and approximately 150–250 nm in diameter, show significant enhancement of target specificity to tumor cells by additions of F3 and CGKRK THPs. We...

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Detalhes bibliográficos
Main Authors: Numata, Keiji, Reagan, Michaela R, Goldstein, Robert H, Rosenblatt, Michael, Kaplan, David L
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157559/
https://ncbi.nlm.nih.gov/pubmed/21739966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200170u
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