Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene (MURC) as a Causal Gene for Familial Dilated Cardiomyopathy

BACKGROUND: Dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM) are classic forms of systolic and diastolic heart failure, respectively. Mutations in genes encoding sarcomere and cytoskeletal proteins are major causes of HCM and DCM. MURC, encoding muscle-restricted coiled-coil, a Z l...

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Main Authors: Rodriguez, Gabriela, Ueyama, Tomomi, Ogata, Takehiro, Czernuszewicz', Grazyna, Tan, Yanli, Dorn, Gerald W., Bogaev, Roberta, Amano, Katsuya, Oh, Hidemasa, Matsubara, Hiroaki, Willerson, James T., Marian, Ali J.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157556/
https://ncbi.nlm.nih.gov/pubmed/21642240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.959866
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