Stage-Specific Remodeling of Atherosclerotic Lesions upon Cholesterol Lowering in LDL Receptor Knockout Mice

Reducing the concentration of circulating lipids leads to decreased cardiovascular morbidity and mortality, but the dynamic remodeling that established atherosclerotic lesions undergo upon lipid lowering is poorly understood. Early or advanced lesions in the aortic root were induced by feeding LDL r...

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Autori principali: Zhao, Ying, Ye, Dan, Wang, Jun, Calpe-Berdiel, Laura, Azzis, Saaleha B.R.N., Van Berkel, Theo J.C., Van Eck, Miranda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157208/
https://ncbi.nlm.nih.gov/pubmed/21741939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.020
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