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KISS1 Methylation and Expression as Tumor Stratification Biomarkers and Clinical Outcome Prognosticators for Bladder Cancer Patients

KISS1 is a metastasis suppressor gene that is lost in several malignancies, including bladder cancer. We tested the epigenetic silencing hypothesis and evaluated the biological influence of KISS1 methylation on its expression and clinical relevance in bladder cancer. KISS1 hypermethylation was frequ...

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Detalhes bibliográficos
Main Authors: Cebrian, Virginia, Fierro, Marta, Orenes-Piñero, Esteban, Grau, Laura, Moya, Patricia, Ecke, Thorsten, Alvarez, Miguel, Gil, Marta, Algaba, Ferran, Bellmunt, Joaquin, Cordon-Cardo, Carlos, Catto, James, López-Beltrán, Antonio, Sánchez-Carbayo, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157173/
https://ncbi.nlm.nih.gov/pubmed/21683672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.009
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