KISS1 Methylation and Expression as Tumor Stratification Biomarkers and Clinical Outcome Prognosticators for Bladder Cancer Patients

KISS1 is a metastasis suppressor gene that is lost in several malignancies, including bladder cancer. We tested the epigenetic silencing hypothesis and evaluated the biological influence of KISS1 methylation on its expression and clinical relevance in bladder cancer. KISS1 hypermethylation was frequ...

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Main Authors: Cebrian, Virginia, Fierro, Marta, Orenes-Piñero, Esteban, Grau, Laura, Moya, Patricia, Ecke, Thorsten, Alvarez, Miguel, Gil, Marta, Algaba, Ferran, Bellmunt, Joaquin, Cordon-Cardo, Carlos, Catto, James, López-Beltrán, Antonio, Sánchez-Carbayo, Marta
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157173/
https://ncbi.nlm.nih.gov/pubmed/21683672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.009
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