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Excessive amounts of mu heavy chain block B-cell development
Antigen-independent B-cell development occurs in several stages that depend on the expression of Ig heavy and light chain. We identified a line of mice that lacked mature B cells in the spleen. This mouse line carried approximately 11 copies of a transgene of the murine heavy chain constant region l...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157007/ https://ncbi.nlm.nih.gov/pubmed/21727177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr049 |
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