Hypercholesterolemia and Chronic Ischemia Alter Myocardial Responses to Selective Cyclooxygenase-2 Inhibition

OBJECTIVE: Cyclooxygenase-2 inhibitors have been implicated in adverse cardiac events. We hypothesize that hypercholesterolemia and ischemia may alter the myocardial response to the cyclooxygenase-2 inhibitor celecoxib. METHODS: Yorkshire swine fed normal chow (CX, n=6) or high-cholesterol diet (HCX...

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Hlavní autoři: Chu, Louis M., Robich, Michael P., Lassaletta, Antonio, Burgess, Thomas, Liu, Yuhong, Sellke, Nicholas, Sellke, Frank W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156971/
https://ncbi.nlm.nih.gov/pubmed/21762932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2011.06.005
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