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In vitro and In vivo Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 Against Multiple Myeloma Cells

PURPOSE: The success of bortezomib therapy for treatment of multiple myeloma (MM) led to the development of structurally and pharmacologically distinct novel proteasome inhibitors. In the present study, we evaluated the efficacy of one such novel orally bioactive proteasome inhibitor MLN9708/MLN2238...

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書誌詳細
主要な著者: Chauhan, Dharminder, Tian, Ze, Zou, Bin, Kuhn, Deborah, Orlowski, Robert, Raje, Noopur, Richardson, Paul, Anderson, Kenneth C.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156932/
https://ncbi.nlm.nih.gov/pubmed/21724551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0476
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