The Glycan Shield of HIV Is Predominantly Oligomannose Independently of Production System or Viral Clade

The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...

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Main Authors: Bonomelli, Camille, Doores, Katie J., Dunlop, D. Cameron, Thaney, Victoria, Dwek, Raymond A., Burton, Dennis R., Crispin, Max, Scanlan, Christopher N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156772/
https://ncbi.nlm.nih.gov/pubmed/21858152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023521
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