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Normal Human Pluripotent Stem Cell Lines Exhibit Pervasive Mosaic Aneuploidy
Human pluripotent stem cell (hPSC) lines have been considered to be homogeneously euploid. Here we report that normal hPSC – including induced pluripotent - lines are karyotypic mosaics of euploid cells intermixed with many cells showing non-clonal aneuploidies as identified by chromosome counting,...
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| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156708/ https://ncbi.nlm.nih.gov/pubmed/21857983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023018 |
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