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Escherichia Coli Fpg Glycosylase is Nonrendundant and Required for the Rapid Global Repair of Oxidized Purine and Pyrimidine Damage In Vivo

Endonuclease III (Endo III) and Formamidopyrimidine-N-glycosylase (Fpg) are two of the predominant DNA glycosylases in E. coli that remove oxidative base damage. In cell extracts and purified form, Endo III is generally more active on oxidized pyrimidines, while Fpg is more active towards oxidized p...

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Autori principali: Schalow, Brandy J., Courcelle, Charmain T, Courcelle, Justin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156590/
https://ncbi.nlm.nih.gov/pubmed/21601577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.004
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