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c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

Intracellular bacterial pathogens, such as Listeria monocytogenes, are detected in the cytosol of host immune cells. Induction of this host response is often dependent on microbial secretion systems, and in L. monocytogenes, is dependent on multi-drug efflux pumps (MDRs). Using L. monocytogenes muta...

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Detalhes bibliográficos
Main Authors: Woodward, Joshua J., Iavarone, Anthony T., Portnoy, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156580/
https://ncbi.nlm.nih.gov/pubmed/20508090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189801
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