Mice Lacking the Type I Interferon Receptor Are Resistant to Listeria monocytogenes

Listeria monocytogenes is a facultative intracellular pathogen that induces a cytosolic signaling cascade resulting in expression of interferon (IFN)-β. Although type I IFNs are critical in viral defense, their role in immunity to bacterial pathogens is much less clear. In this study, we addressed t...

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Autori principali: Auerbuch, Victoria, Brockstedt, Dirk G., Meyer-Morse, Nicole, O'Riordan, Mary, Portnoy, Daniel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
Soggetti:
Brief Definitive Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211930/
https://ncbi.nlm.nih.gov/pubmed/15302899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040976
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