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PHOSPHORYLATION OF Y372 IS CRITICAL FOR JAK2 TYROSINE KINASE ACTIVATION
Jak2 tyrosine kinase plays an important role in cytokine mediated signal transduction. There are 49 tyrosine residues in Jak2 and phosphorylation of some of these are known to play important roles in the regulation of Jak2 kinase activity. Here, using mass spectrometry, we identified tyrosine residu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156348/ https://ncbi.nlm.nih.gov/pubmed/21726629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.06.015 |
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