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Multidrug resistance reversal by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes

One of the major obstacles to the success of cancer chemotherapy is the multidrug resistance (MDR) often resulting due to the overexpression of drug efflux transporter pumps such as P-glycoprotein (P-gp). Highly efficacious third generation P-gp inhibitors, like tariquidar, have shown promising resu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patel, Niravkumar R., Rathi, Alok, Mongayt, Dmitriy, Torchilin, Vladimir P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156341/
https://ncbi.nlm.nih.gov/pubmed/21703341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.05.082
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