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Chinese origin rhesus macaque major histocompatibility complex class I molecules promiscuously present epitopes from SIV associated with molecules of Indian origin; implications for immunodominance and viral escape

The presentation of identical peptides by different major histocompatibility complex class I (MHC-I) molecules, termed promiscuity, is a controversial feature of T cell-mediated immunity to pathogens. The astounding diversity of MHC-I molecules in human populations, presumably to enable binding of e...

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Detalhes bibliográficos
Main Authors: Maness, Nicholas James, Walsh, Andrew D., Rudersdorf, Richard A., Erickson, Priscilla A., Piaskowski, Shari M., Wilson, Nancy A., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156284/
https://ncbi.nlm.nih.gov/pubmed/21626440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0538-4
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