Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

The homeostatic control mechanisms regulating human leukocyte numbers are poorly understood. Here, we assessed the role of phagocytes in this process using human immune system (HIS) BALB/c Rag2(−/−)IL-2Rγc(−/−) mice in which human leukocytes are generated from transplanted hematopoietic progenitor c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Legrand, Nicolas, Huntington, Nicholas D., Nagasawa, Maho, Bakker, Arjen Q., Schotte, Remko, Strick-Marchand, Hélène, de Geus, Sandra J., Pouw, Stephan M., Böhne, Martino, Voordouw, Arie, Weijer, Kees, Di Santo, James P., Spits, Hergen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156191/
https://ncbi.nlm.nih.gov/pubmed/21788504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101398108
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