Soluble Beta-Amyloid Precursor Protein Is Related to Disease Progression in Amyotrophic Lateral Sclerosis

BACKGROUND: Biomarkers of disease progression in amyotrophic lateral sclerosis (ALS) could support the identification of beneficial drugs in clinical trials. We aimed to test whether soluble fragments of beta-amyloid precursor protein (sAPPα and sAPPß) correlated with clinical subtypes of ALS and we...

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Autori principali: Steinacker, Petra, Fang, Lubin, Kuhle, Jens, Petzold, Axel, Tumani, Hayrettin, Ludolph, Albert C., Otto, Markus, Brettschneider, Johannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156148/
https://ncbi.nlm.nih.gov/pubmed/21858182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023600
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