Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis

BACKGROUND: Aryl hydrocarbon receptor (AhR), a transcription factor of the bHLH/PAS family, is well characterized to regulate the biochemical and toxic effects of environmental chemicals. More recently, AhR activation has been shown to regulate the differentiation of Foxp3(+) Tregs as well as Th17 c...

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Bibliographic Details
Main Authors: Singh, Narendra P., Singh, Udai P., Singh, Balwan, Price, Robert L., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156147/
https://ncbi.nlm.nih.gov/pubmed/21858153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023522
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