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A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis
Gene function during embryogenesis is typically defined by loss-of-function experiments, for example by targeted mutagenesis (knockout) in the mouse. In the zebrafish model, effective reverse genetic techniques have been developed using microinjection of gene-specific antisense morpholinos. Morpholi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156006/ https://ncbi.nlm.nih.gov/pubmed/20736915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2020 |
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