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Cytotoxicity of aporphines in human colon cancer cell lines HCT-116 and Caco-2: an SAR study

A series of synthetic aporphine derivatives structurally related to domesticine and nantenine (ring A, N6 and ring C truncated analogs), was evaluated in MTS cytotoxicity assays against the human colon cancer cell lines, HCT-116 and Caco-2. In general, the C1 position of ring A is tolerant of alkoxy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ponnala, Shashikanth, Chaudhary, Sandeep, González-Sarrias, Antonio, Seeram, Navindra P., Harding, Wayne W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155955/
https://ncbi.nlm.nih.gov/pubmed/21724394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.06.005
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